Shuqun Zhang Selected Research

Therapeutics

4/2024	Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening.
3/2024	Establishment of patient-derived organoids for guiding personalized therapies in breast cancer patients.
3/2024	The Efficiency and Toxicity Of Anlotinib in Combination With Docetaxel Followed by Epirubicin and Cyclophosphamide Regimen as Neoadjuvant Treatment in IIB to IIIA Triple Negative Breast Cancer: A Single-Arm, Multicenter, Open-Label, Phase II Study.
2/2024	Machine learning predicts the risk of osteoporosis in patients with breast cancer and healthy women.
1/2024	GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress.
12/2023	High dose Vitamin C inhibits PD-L1 by ROS-pSTAT3 signal pathway and enhances T cell function in TNBC.
10/2022	Clinicopathological characteristics and prognostic analysis of PIK3CA mutation in breast cancer patients in Northwest China.
1/2022	Computational simulation studies on the binding selectivity of Wee1 and Checkpoint kinase 1 by molecular dynamics simulation combined with free energy calculations.
1/2022	Comprehensive pan-cancer analysis of N7-methylguanosine regulators: Expression features and potential implications in prognosis and immunotherapy.
1/2019	Fulvestrant 500 mg Versus Exemestane in Postmenopausal Women With Metastatic Breast Cancer Resistant to Adjuvant Nonsteroidal Aromatase Inhibitors in Clinical Practice: A Multicenter Retrospective Study.

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Shuqun Zhang Research Topics

Disease

51	Neoplasms (Cancer) 05/2024 - 05/2014
35	Breast Neoplasms (Breast Cancer) 03/2024 - 05/2014
17	Neoplasm Metastasis (Metastasis) 01/2023 - 05/2014
10	Infections 05/2024 - 11/2003
5	Colorectal Neoplasms (Colorectal Cancer) 02/2023 - 12/2014
4	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 11/2019
3	Hypoxia (Hypoxemia) 01/2022 - 01/2021
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 12/2019
3	Starvation 01/2020 - 01/2015
3	Alzheimer Disease (Alzheimer's Disease) 04/2017 - 05/2016
2	Triple Negative Breast Neoplasms 03/2024 - 01/2024
2	Brain Neoplasms (Brain Tumor) 10/2023 - 04/2023
2	Adenocarcinoma of Lung 01/2022 - 01/2021
2	Lymphatic Metastasis 02/2020 - 05/2016
2	Disease Resistance 01/2020 - 08/2002
2	Esophageal Squamous Cell Carcinoma 12/2019 - 10/2014
1	Osteoporosis 02/2024
1	Pathologic Complete Response 02/2024
1	Cognitive Dysfunction 10/2023
1	Chemotherapy-Related Cognitive Impairment 10/2023
1	Obesity 10/2023
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2023
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2023
1	Neuralgia (Stump Neuralgia) 01/2023
1	Ductal Carcinoma 01/2023
1	Diarrhea 12/2022
1	Neutropenia 12/2022
1	Immune System Diseases (Immune Disorders) 12/2022

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 02/2024 - 04/2011
8	Biomarkers (Surrogate Marker)IBA 03/2024 - 08/2017
6	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2017
5	baicaleinIBA 10/2023 - 01/2016
5	Messenger RNA (mRNA)IBA 12/2019 - 05/2014
4	Long Noncoding RNAIBA 02/2023 - 01/2021
4	Phenobarbital (Luminal)FDA Link 01/2023 - 02/2020
4	sinomenineIBA 01/2022 - 08/2015
3	Transcription Factors (Transcription Factor)IBA 05/2024 - 08/2015
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2024 - 01/2022
3	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2022
3	camalexinIBA 01/2020 - 04/2008
3	CateninsIBA 02/2018 - 07/2015
3	ethyleneIBA 01/2015 - 11/2003
2	Docetaxel (Taxotere)FDA Link 03/2024 - 12/2022
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/2024 - 10/2023
2	Hormones (Hormone)IBA 02/2024 - 09/2021
2	Guanosine Triphosphate (GTP)IBA 10/2023 - 04/2023
2	NucleotidesIBA 10/2023 - 01/2022
2	LeptinIBA 10/2023 - 01/2016
2	Caspase 8 (Caspase-8)IBA 01/2022 - 01/2021
2	Dasatinib (BMS 354825)FDA Link 01/2022 - 01/2021
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2022 - 01/2022
2	6-methyladenineIBA 01/2022 - 01/2022
2	5-Methylcytosine (5 Methylcytosine)IBA 01/2022 - 01/2022
2	EnzymesIBA 11/2021 - 05/2016
2	Matrix Metalloproteinases (MMPs)IBA 02/2020 - 01/2016
2	ORALIT (ORS)IBA 07/2017 - 01/2016
2	AcetylcholinesteraseIBA 11/2016 - 05/2016
2	Protein Kinases (Protein Kinase)IBA 07/2014 - 08/2002
2	Mitogen-Activated Protein KinasesIBA 07/2014 - 03/2008
1	Keratan SulfateIBA 05/2024
1	GlycosaminoglycansIBA 05/2024
1	Protons (Proton)IBA 03/2024
1	Epirubicin (Ellence)FDA LinkGeneric 03/2024
1	anlotinibIBA 03/2024
1	Small Cytoplasmic RNAIBA 01/2024
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 12/2023
1	Immunologic Factors (Immunomodulators)IBA 12/2023
1	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 10/2023
1	InflammasomesIBA 10/2023
1	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2023
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 06/2023
1	PlatinumIBA 06/2023
1	130-nm albumin-bound paclitaxelIBA 01/2023
1	Glia Maturation Factor (GMF)IBA 01/2023
1	Actin Depolymerizing Factors (Cofilins)IBA 01/2023
1	AlkaloidsIBA 01/2023
1	Epoxide HydrolasesIBA 01/2023
1	Estrogens (Estrogen)FDA Link 01/2023
1	cyclovirobuxine DIBA 01/2023
1	pyrotinibIBA 12/2022
1	Capecitabine (Xeloda)FDA Link 12/2022
1	Trastuzumab (Herceptin)FDA Link 12/2022
1	Formaldehyde (Formol)FDA Link 10/2022
1	DNA (Deoxyribonucleic Acid)IBA 10/2022
1	Indicators and Reagents (Reagents)IBA 10/2022
1	ParaffinIBA 10/2022
1	MAP Kinase Kinase Kinase 5IBA 08/2022
1	Pathogen-Associated Molecular Pattern MoleculesIBA 08/2022
1	Cisplatin (Platino)FDA LinkGeneric 01/2022
1	CaspasesIBA 01/2022
1	LigandsIBA 01/2022

Therapy/Procedure

12	Therapeutics 04/2024 - 05/2014
8	Drug Therapy (Chemotherapy) 01/2024 - 01/2019
7	Immunotherapy 04/2024 - 07/2021
3	Neoadjuvant Therapy 03/2024 - 01/2022
2	Radiotherapy 01/2023 - 12/2019
1	Duration of Therapy 02/2024
1	Intravenous Administration 12/2023
1	Punctures 11/2023
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2023